Limb-girdle muscular dystrophy

Limb-girdle muscular dystrophy (LGMD) refers to a group of more than 20 types of muscular dystrophy that primarily affect the muscles around the hips (pelvic girdle) and shoulders (shoulder girdle).

LGMD is characterised by progressive weakness and wasting of the muscles in these areas. Over time, this may extend to the legs. Some individuals also experience joint pain or sore muscles. Progression varies from person to person, even between siblings.

The condition gets its name from the “limb girdles,” which are the muscle groups surrounding the shoulder and hip bones. It affects the muscles connected to these areas, leading to weakness and muscle loss.

Limb Girdle Muscular Dystrophy

Symptoms

Symptoms of LGMD can vary widely, but may include:

Difficulty climbing stairs or standing from a seated position
Trouble lifting the arms or reaching overhead
Frequent falls or poor balance
Muscle pain or soreness
Joint pain or stiffness
Fatigue during everyday activities
Waddling gait or changes in walking pattern

Not all symptoms appear at once, and their severity and rate of progression differ between individuals.

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